Infusion is usually outpatient with 1–2 days rest. Motor change — reduced spasticity, better voluntary control — unfolds over weeks to months if it occurs, and children usually intensify physiotherapy during and after. Brain reorganisation is slow and incomplete in established cerebral palsy. There is no period in which the condition reverses; ongoing rehabilitation remains standard.
Forty-one registered trials and 2 recruiting studies investigate stem-cell approaches in cerebral palsy, mostly in Asia and Latin America. Small cohorts describe reduced muscle tone and improved gross-motor scores within 3–12 months; most lack adequate controls or blinding. Placebo effects in rehabilitation are substantial, and concurrent physiotherapy confounds attribution. No large randomised trial has shown stem cells superior to intensive physiotherapy or established interventions; few studies follow beyond 12 months.
Am I a candidate? → · Cerebral Palsy: full overview → · Cerebral Palsy cost → · Cost →
Medically reviewed by StemCellAtlas’s editorial team with Kiian Nadiia, MD, PhD (Paediatric Neurologist · Medical Director, CSM Clinic Network · 12+ yrs in Autism Spectrum Disorders) of partner clinic Stem Plus (Sofia), against ISSCR, FDA & EMA guidance. Educational information, not medical advice; figures indicative.
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