Creatine with GLP-1: the trial
Creatine during GLP-1 treatment is being tested directly. NCT07625202 compares creatine with placebo during resistance training, with 40 participants planned. The record retrieved on 30 August 2026 lists recruitment and no posted results. It is a study to follow, not yet a result showing that creatine prevents muscle loss.
NCT07625202 at a glance
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| Field | Retrieved record |
|---|---|
| Participants | 40 estimated |
| Status | Recruiting |
| Comparison | Creatine vs placebo; resistance training |
| Primary outcome | Sit-to-stand performance, 12 weeks |
| Lean tissue | Secondary DXA outcome, 12 weeks |
| Posted results | None in the retrieved record |
Function and tissue are separate outcomes
The primary test counts repeated sit-to-stand movements. The DXA lean-tissue measure is secondary. This distinction matters when a headline calls the trial a “muscle study”: a change in physical performance is not automatically a change in tissue mass, or vice versa.
Creatine is not the only part of the study
Resistance training is part of the study design. Any eventual result must be read in that context; this is not a trial of a supplement replacing exercise. The trial record gives the arms and outcomes needed to check what was actually tested.
What would change this answer?
A completed result with participant numbers, between-group differences and adverse-event reporting would answer more than a registry plan. For now, “40” is estimated enrollment and the record contains no posted results. The source link opens the current registry, which may change after this snapshot.

Use the table and its sources
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Source-linked editorial synthesis, prepared with AI assistance. This is not a clinician review or a personalised treatment recommendation. Corrections: editorial standards.