How many stem-cell trials for Heart Failure & Cardiac Repair are recruiting right now?
As of 2026-08-29: 10 open studies against 125 registrations overall, or 8% of the historical total.
Who these studies will actually take
Trials require an ejection-fraction ceiling, optimised guideline-directed medical therapy for a defined period, and often a recent hospitalisation. Being on suboptimal medication is a screen failure, because the trial must show benefit on top of proper treatment.
The studies currently enrolling
| Study | Phase | Status | Planned n | Lead sponsor | Start |
|---|---|---|---|---|---|
| NCT06560762 — Study in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) | Phase 1 | Recruiting | 12 | Secretome Therapeutics | 2025-03-03 |
| NCT07265349 — A Phase I/II Clinical Trial of Intramyocardial Injection of HucMSCs for the Treatment of Chronic Heart Failure | Phase 1, Phase 2 | Recruiting | 51 | Tasly Pharmaceutical Group Co., Ltd | 2025-12-26 |
| NCT03394365 — A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Ri | Phase 3 | Recruiting | 115 | Pierre Fabre Medicament | 2017-12-29 |
| NCT07496372 — A Pivotal Clinical Trial of Human Induced Pluripotent Stem Cell-derived Cardiomyocytes Injection (HiCM-188) for the Treatment of Advanced Heart Failur | Phase 3 | Recruiting | 80 | HELP Therapeutics Co., Ltd. | 2026-04-30 |
| NCT06154044 — Cell Therapy and Myocardial Recovery in Heart Failure Patients Undergoing Left Ventricular Assist Device Support | Phase 2 | Recruiting | 10 | University Medical Centre Ljubljana | 2022-05-01 |
| NCT05647213 — Autologous Induced Pluripotent Stem Cells of Cardiac Lineage for Congenital Heart Disease | Phase 1 | Recruiting | 50 | HeartWorks, Inc. | 2023-02-03 |
| NCT07192211 — Exploratory Study of ADR-002K for Heart Failure Patients With Ischemic Heart Disease Who Undergo CABG | Phase 2 | Recruiting | 50 | Rohto Pharmaceutical Co., Ltd. | 2026-04-28 |
| NCT04396899 — Safety and Efficacy of Induced Pluripotent Stem Cell-derived Engineered Human Myocardium as Biological Ventricular Assist Tissue in Terminal Heart Fai | Phase 1, Phase 2 | Recruiting | 53 | University Medical Center Goettingen | 2020-02-03 |
What recruiting does and does not mean
The status field tracks paperwork, not promise. What matters underneath it is the eligibility list, the outcome measures the sponsor committed to, and whether a site near you is actually enrolling, all of which sit on the registry record itself.
Sites sit in 32 countries, led by United States. Travelling for a trial rarely works unless the site has confirmed in writing that it can enrol non-residents and fund the follow-up schedule.
Who is running the studies here
Lead sponsors appearing most often for this condition. Useful for one specific check: whether the entity quoting research at you appears anywhere in it.
- HELP Therapeutics Co., Ltd. — 8 registered records
- University Medical Centre Ljubljana — 7 registered records
- JKastrup — 4 registered records
- Johann Wolfgang Goethe University Hospital — 3 registered records
- Losordo, Douglas, M.D. — 3 registered records
- The University of Texas Health Science Center, Houston — 2 registered records
Frequently asked
How many stem-cell trials for Heart Failure & Cardiac Repair are recruiting right now?
10 of 125 registered records (2026-08-29).
Can I join one of these trials?
Eligibility is decided by the protocol, not by willingness to pay. Read the inclusion and exclusion list on the registry record, then contact the coordinator named there.
Do trials charge participants?
Participants are not usually billed for the study product. A five-figure invoice attached to a supposed trial place means you are buying a treatment, not joining research.
Registry and literature counts retrieved 2026-08-29 (ClinicalTrials.gov API v2; PubMed E-utilities). Registration or publication volume measures research activity, not effectiveness or approval. Educational information — not medical advice; verify product, indication, legal pathway and evidence with an independent qualified physician. Page generated 2026-08-29. See our editorial standards.
More on this condition
- Heart Failure & Cardiac Repair: cell-therapy evidence and registered trials
- How much does stem cell therapy for Heart Failure & Cardiac Repair cost? (2026)
- Heart Failure & Cardiac Repair stem cell therapy — your questions answered (2026)
- Heart Failure & Cardiac Repair: cell-therapy evidence by therapy class
- MSC vs HSCT for Heart Failure & Cardiac Repair: what the registries show