Which countries run stem-cell trials for Knee Osteoarthritis?

Country distribution

A study with sites in several countries is counted once per country, taken from the location block of each registry record.

What the map means for Knee Osteoarthritis

Registrations spread widely across East Asia, North America and Europe, reflecting both research interest and a very large private orthobiologics market. That breadth makes country choice a poor proxy for quality here; the product and the protocol matter far more.

Where recruitment is actually open

What travelling for a trial actually involves

Cross-border participation fails on logistics more often than on eligibility: follow-up schedules, local insurance, visa duration and who pays for complications. A site that cannot answer those in writing is not going to enrol you.

Multi-country studies, named

Registered studies with sites in more than one country — the clearest evidence of collaboration rather than a single-centre series.

• NCT06576583 — Implantation of Engineered Cartilage Grafts for Treatment of Patellofemoral Osteoarthritis Versus Surgical Comparators. (Austria, Croatia, Germany, Italy, Netherlands, Poland)

Why trial geography is not a shortlist

Where studies happen reflects who funds and who authorises them. Treating that as a ranking of care quality confuses the research system with the treatment market, two things that overlap far less than medical-tourism marketing implies.

Before treating geography as a shortlist, read the legality overview by country and what "best country" actually means here.

When these studies started

Registrations by start year since 2020: 2020 (12), 2021 (8), 2022 (13), 2023 (12), 2024 (10), 2025 (8), 2026 (6). Activity for this condition spans 2007 to 2026, which shows whether interest is growing, flat or past its peak.

Frequently asked

Which countries run stem-cell trials for Knee Osteoarthritis?

Sites are registered in 43 countries; the largest is United States (~32% of country mentions, 2026-08-29).

Does a country with many trials mean better treatment there?

No. Registration volume reflects the research and regulatory environment, not the quality of care a private clinic there will provide.

Are trial sites and commercial clinics the same thing?

Mostly no. Some clinics imply an association with local research institutions; the registry record names the actual sponsor and site, which settles it.

Registry and literature counts retrieved 2026-08-29 (ClinicalTrials.gov API v2; PubMed E-utilities). Registration or publication volume measures research activity, not effectiveness or approval. Educational information — not medical advice; verify product, indication, legal pathway and evidence with an independent qualified physician. Page generated 2026-08-29. See our editorial standards.