How many stem-cell trials for Lupus (SLE) are recruiting right now?
5 of 44 registered studies were open to enrolment in the 2026-08-29 snapshot — 11% of everything ever registered for this condition with a stem-cell intervention.
Who these studies will actually take
Trials require serological and clinical activity above a threshold, often refractory to standard immunosuppression, with organ-specific criteria for renal involvement. Stable, well-controlled disease is excluded — the trial needs measurable activity.
The studies currently enrolling
| Study | Phase | Status | Planned n | Lead sponsor | Start |
|---|---|---|---|---|---|
| NCT06058078 — RY_SW01 Cell Injection Therapy in Active Lupus Nephritis | Phase 2 | Recruiting | 60 | Jiangsu Renocell Biotech Company | 2023-08-17 |
| NCT03673748 — Treatment of Lupus Nephritis With Allogeneic Mesenchymal Stem Cells | Phase 2 | Recruiting | 20 | Red de Terapia Celular | 2022-12-27 |
| NCT05029336 — Autologous Stem Cell Transplant (ASCT) for Autoimmune Diseases | Phase 2 | Recruiting | 20 | Stephan Grupp MD PhD | 2026-03 |
| NCT07041801 — Treatment of Systemic Lupus Erythematosus With Human Umbilical Cord Mesenchymal Stem Cells | Phase 1, Phase 2 | Recruiting | 58 | Shenzhen Beike Bio-Technology Co., Ltd. | 2025-06-28 |
| NCT05508009 — Early Trial of Allogeneic Hematopoietic Stem Cell Transplantation for Patients Who Will Receive a Kidney Transplant From the Same Donor | Phase 1, Phase 2 | Recruiting | 12 | Alice Bertaina | 2023-01-10 |
What recruiting does and does not mean
Open enrolment is an administrative state, not a clinical endorsement. Sponsors register before recruiting, keep records open through slow periods and close them late. Read the eligibility section and the last-update date together before drawing any conclusion.
Sites sit in 10 countries, led by United States. Travelling for a trial rarely works unless the site has confirmed in writing that it can enrol non-residents and fund the follow-up schedule.
Who is running the studies here
Lead sponsors appearing most often for this condition. Useful for one specific check: whether the entity quoting research at you appears anywhere in it.
- Northwestern University — 3 registered records
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School — 2 registered records
- Medical University of South Carolina — 2 registered records
- Federal University of São Paulo — 2 registered records
- Corestemchemon, Inc. — 2 registered records
- Chinese PLA General Hospital — 1 registered record
Frequently asked
How many stem-cell trials for Lupus (SLE) are recruiting right now?
5 of 44 registered records (2026-08-29).
Can I join one of these trials?
That depends entirely on the written criteria — age, disease stage, prior treatment and often geography. The site's study coordinator is the only reliable source on current capacity.
Do trials charge participants?
Legitimate registered trials do not normally charge for the investigational intervention. Being asked for a large fee to enrol is a strong warning sign.
Registry and literature counts retrieved 2026-08-29 (ClinicalTrials.gov API v2; PubMed E-utilities). Registration or publication volume measures research activity, not effectiveness or approval. Educational information — not medical advice; verify product, indication, legal pathway and evidence with an independent qualified physician. Page generated 2026-08-29. See our editorial standards.