Which countries run stem-cell trials for ALS (Motor Neurone Disease)?
Sampled registrations place sites in 16 countries. United States is the largest single contributor at roughly 35% of country mentions. Snapshot 2026-08-29.
Country distribution
| Country | Studies with a site there |
|---|---|
| United States | 19 |
| China | 6 |
| Iran | 5 |
| Israel | 5 |
| Spain | 5 |
| South Korea | 5 |
| Italy | 3 |
| Brazil | 2 |
| Japan | 2 |
| Poland | 2 |
A study with sites in several countries is counted once per country, taken from the location block of each registry record.
What the map means for ALS (Motor Neurone Disease)
ALS cell research concentrates in a handful of academic neurology centres with the neurosurgical and intensive-care backup that intrathecal or intraspinal delivery demands. Clinics offering intravenous infusions for ALS in tourism destinations are not delivering the intervention these centres are studying, whatever the marketing suggests.
Where recruitment is actually open
| Country | Open studies with a site there |
|---|---|
| United States | 3 |
| China | 3 |
| Israel | 2 |
| Italy | 2 |
| United Arab Emirates | 1 |
| Canada | 1 |
What travelling for a trial actually involves
If a site is abroad, the practical questions are who provides follow-up at home, what happens if an adverse event occurs after you fly back, and whether the protocol permits remote assessment at all. Most do not.
Multi-country studies, named
Registered studies with sites in more than one country — the clearest evidence of collaboration rather than a single-centre series.
- NCT06665165 — AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis (Canada, United States)
- NCT02795052 — Neurologic Stem Cell Treatment Study (United Arab Emirates, United States)
Why trial geography is not a shortlist
Registration geography is a proxy for research infrastructure, not for outcomes. The relevant question about any destination is what oversight applies to the specific product you would receive there, which is a different enquiry entirely.
Before treating geography as a shortlist, read the legality overview by country and what "best country" actually means here.
When these studies started
Registrations by start year since 2020: 2020 (1), 2021 (2), 2022 (2), 2023 (1), 2024 (4), 2025 (10), 2026 (1). Activity for this condition spans 2007 to 2026, which shows whether interest is growing, flat or past its peak.
Frequently asked
Which countries run stem-cell trials for ALS (Motor Neurone Disease)?
Sites are registered in 16 countries; the largest is United States (~35% of country mentions, 2026-08-29).
Does a country with many trials mean better treatment there?
No — trial counts describe where research is permitted and paid for. Care quality is decided at the level of the individual provider and product.
Are trial sites and commercial clinics the same thing?
Usually not. The hospital running a registered study is often unrelated to clinics marketing treatments to international patients in the same city.
Registry and literature counts retrieved 2026-08-29 (ClinicalTrials.gov API v2; PubMed E-utilities). Registration or publication volume measures research activity, not effectiveness or approval. Educational information — not medical advice; verify product, indication, legal pathway and evidence with an independent qualified physician. Page generated 2026-08-29. See our editorial standards.
More on this condition
- ALS (Motor Neurone Disease): cell-therapy evidence and registered trials
- How much does stem cell therapy for ALS (Motor Neurone Disease) cost? (2026)
- ALS (Motor Neurone Disease) stem cell therapy — your questions answered (2026)
- ALS (Motor Neurone Disease): cell-therapy evidence by therapy class
- MSC vs HSCT for ALS (Motor Neurone Disease): what the registries show