How many stem-cell trials for ALS (Motor Neurone Disease) are recruiting right now?
10 of 65 registered studies were open to enrolment in the 2026-08-29 snapshot — 15% of everything ever registered for this condition with a stem-cell intervention.
Who these studies will actually take
ALS trials typically enrol within a defined window after symptom onset, with a minimum forced vital capacity and a functional score above a floor — which excludes many people by the time they start searching. Sites also limit travel-in participants because repeat intrathecal dosing and monitoring require local follow-up.
The studies currently enrolling
| Study | Phase | Status | Planned n | Lead sponsor | Start |
|---|---|---|---|---|---|
| NCT02795052 — Neurologic Stem Cell Treatment Study | n/a | Recruiting | 500 | MD Stem Cells | 2016-06 |
| NCT06598202 — Exploring Nasal Drop Therapy With Small Extracellular Vesicles for ALS | Phase 1, Phase 2 | Recruiting | 38 | Xuanwu Hospital, Beijing | 2024-12-01 |
| NCT00801333 — Derivation of Induced Pluripotent Stem Cells From an Existing Collection of Human Somatic Cells | n/a | Recruiting | 25 | Hadassah Medical Organization | 2008-11 |
| NCT06765564 — Clinical Study of Induced Pluripotent Stem Cells Derived Motor Neuron Precursor Cell Therapy for Amyotrophic Lateral Sclerosis (ALS) | n/a | Recruiting | 3 | Shanghai East Hospital | 2024-03-13 |
| NCT07118319 — The Safety, Tolerability and Preliminary Efficacy of Derived Motor Neuron Progenitor Cells (XS228CN) in Subjects With Amyotrophic Lateral Sclerosis | Phase 1 | Recruiting | 12 | XellSmart Bio-Pharmaceutical (Suzhou) Co., Ltd. | 2025-09-15 |
| NCT06551649 — Human Amniotic Mesenchymal Cell Secretome for Neurodegeneration and Neuroinflammation | n/a | Recruiting | 60 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 2025-01-17 |
| NCT00874783 — Development of IPS from Donated Somatic Cells of Patients with Neurological Diseases | n/a | Recruiting | 120 | Hadassah Medical Organization | 2009-04 |
| NCT06344260 — Neural Stem Cell Treatment for Amyotrophic Lateral Sclerosis (STEMALS) | Phase 2 | Recruiting | 30 | Casa Sollievo della Sofferenza IRCCS | 2024-01-25 |
What recruiting does and does not mean
The status field tracks paperwork, not promise. What matters underneath it is the eligibility list, the outcome measures the sponsor committed to, and whether a site near you is actually enrolling, all of which sit on the registry record itself.
Sites sit in 16 countries, led by United States. Travelling for a trial rarely works unless the site has confirmed in writing that it can enrol non-residents and fund the follow-up schedule.
Who is running the studies here
Lead sponsors appearing most often for this condition. Useful for one specific check: whether the entity quoting research at you appears anywhere in it.
- Brainstorm-Cell Therapeutics — 6 registered records
- Royan Institute — 4 registered records
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia — 3 registered records
- Hadassah Medical Organization — 3 registered records
- Corestemchemon, Inc. — 3 registered records
- Rapa Therapeutics LLC — 2 registered records
Frequently asked
How many stem-cell trials for ALS (Motor Neurone Disease) are recruiting right now?
10 of 65 registered records (2026-08-29).
Can I join one of these trials?
Only if you meet the published eligibility criteria and the site confirms capacity. Start from the registry record's contact block, not from a clinic advertisement.
Do trials charge participants?
Trial participation is normally free of charge for the intervention under study; some studies even reimburse travel. Payment demands invert that relationship and should stop the conversation.
Registry and literature counts retrieved 2026-08-29 (ClinicalTrials.gov API v2; PubMed E-utilities). Registration or publication volume measures research activity, not effectiveness or approval. Educational information — not medical advice; verify product, indication, legal pathway and evidence with an independent qualified physician. Page generated 2026-08-29. See our editorial standards.
More on this condition
- ALS (Motor Neurone Disease): cell-therapy evidence and registered trials
- How much does stem cell therapy for ALS (Motor Neurone Disease) cost? (2026)
- ALS (Motor Neurone Disease) stem cell therapy — your questions answered (2026)
- ALS (Motor Neurone Disease): cell-therapy evidence by therapy class
- MSC vs HSCT for ALS (Motor Neurone Disease): what the registries show