Question

Which countries run stem-cell trials for Premature Ovarian Insufficiency?

Sampled registrations place sites in 16 countries. China is the largest single contributor at roughly 43% of country mentions. Snapshot 2026-08-29.

Medical review statusMedically reviewedReviewed by: Stem Plus medical teamReviewed on: 2026-08-29Last evidence update: 2026-08-29Methodology and editorial standards
Clinical review team: Dr Kamelia Milcheva, Hematologist · Dr Vadym Uvarov, Board-Certified Physician · Hepatobiliary Surgeon · Candidate of Medical SciencesEditorial responsibility: StemCellAtlas research teamEducational information only. This page does not provide medical advice, diagnosis or a treatment recommendation.

Country distribution

CountryStudies with a site there
China13
Egypt5
United States4
Spain2
Ukraine1
Malta1
North Macedonia1
Serbia1
South Korea1
France1

A study with sites in several countries is counted once per country, taken from the location block of each registry record.

What the map means for Premature Ovarian Insufficiency

Registered studies appear in a small number of reproductive-medicine centres; the commercial market runs through fertility tourism, often bundling injections with IVF cycles so that attribution is impossible.

Where recruitment is actually open

CountryOpen studies with a site there
China2
United Arab Emirates1

What travelling for a trial actually involves

If a site is abroad, the practical questions are who provides follow-up at home, what happens if an adverse event occurs after you fly back, and whether the protocol permits remote assessment at all. Most do not.

Multi-country studies, named

Registered studies with sites in more than one country — the clearest evidence of collaboration rather than a single-centre series.

  • NCT04009473 — Stem Cell Therapy and Growth Factor Ovarian in Vitro Activation (Malta, North Macedonia, Serbia)

Why trial geography is not a shortlist

The map is drawn by policy and money. Permissive or well-defined regulatory pathways attract registrations and large research budgets attract more still. None of that transfers to the private clinic advertising in the same city, which may operate under no comparable supervision.

Before treating geography as a shortlist, read the legality overview by country and what "best country" actually means here.

When these studies started

Registrations by start year since 2020: 2020 (1), 2021 (1), 2023 (2), 2024 (3), 2025 (2), 2026 (5). Activity for this condition spans 2002 to 2026, which shows whether interest is growing, flat or past its peak.

Frequently asked

Which countries run stem-cell trials for Premature Ovarian Insufficiency?

Sites are registered in 16 countries; the largest is China (~43% of country mentions, 2026-08-29).

Does a country with many trials mean better treatment there?

Volume tracks funding and law, not outcomes. The relevant question is what oversight covers the specific clinic and product you are considering.

Are trial sites and commercial clinics the same thing?

Usually not. The hospital running a registered study is often unrelated to clinics marketing treatments to international patients in the same city.

Registry and literature counts retrieved 2026-08-29 (ClinicalTrials.gov API v2; PubMed E-utilities). Registration or publication volume measures research activity, not effectiveness or approval. Educational information — not medical advice; verify product, indication, legal pathway and evidence with an independent qualified physician. Page generated 2026-08-29. See our editorial standards.

Explore all sections · Data & downloads