How many stem-cell trials for Premature Ovarian Insufficiency are recruiting right now?
3 of 36 registered studies were open to enrolment in the 2026-08-29 snapshot — 8% of everything ever registered for this condition with a stem-cell intervention.
Who these studies will actually take
Trials require hormone-confirmed diagnosis, defined amenorrhoea duration and often antral follicle counts. Women with age-related decline rather than true insufficiency are excluded, though commercially the two are routinely merged.
The studies currently enrolling
| Study | Phase | Status | Planned n | Lead sponsor | Start |
|---|---|---|---|---|---|
| NCT07775391 — Phase Ⅰ/Ⅱa Trial Evaluating Intravenous hUC-MSCs Injection for Safety, Tolerability and Efficacy in Patients With POI | Phase 1, Phase 2 | Recruiting | 59 | Shenzhen Wingor Biotechnology Co., Ltd. | 2026-08-03 |
| NCT06841328 — Fertility Enhancement Through Regenerative Treatment in Ovaries and Testes | n/a | Recruiting | 60 | Jumeirah American Clinic | 2025-04-08 |
| NCT07115082 — Clinical Study on the Safety and Efficacy of Human Amniotic Mesenchymal Stem Cells in the Treatment of Premature Ovarian Insufficiency | Phase 1, Phase 2 | Recruiting | 50 | Yan Hongli | 2024-10-15 |
What recruiting does and does not mean
The status field tracks paperwork, not promise. What matters underneath it is the eligibility list, the outcome measures the sponsor committed to, and whether a site near you is actually enrolling, all of which sit on the registry record itself.
Sites sit in 16 countries, led by China. Travelling for a trial rarely works unless the site has confirmed in writing that it can enrol non-residents and fund the follow-up schedule.
Who is running the studies here
Lead sponsors appearing most often for this condition. Useful for one specific check: whether the entity quoting research at you appears anywhere in it.
- Chinese Academy of Sciences — 3 registered records
- Al-Azhar University — 2 registered records
- Li-jun Ding — 2 registered records
- Ukraine Association of Biobank — 1 registered record
- Shenzhen Wingor Biotechnology Co., Ltd. — 1 registered record
- M.D. Anderson Cancer Center — 1 registered record
Frequently asked
How many stem-cell trials for Premature Ovarian Insufficiency are recruiting right now?
3 of 36 registered records (2026-08-29).
Can I join one of these trials?
Eligibility is decided by the protocol, not by willingness to pay. Read the inclusion and exclusion list on the registry record, then contact the coordinator named there.
Do trials charge participants?
Legitimate registered trials do not normally charge for the investigational intervention. Being asked for a large fee to enrol is a strong warning sign.
Registry and literature counts retrieved 2026-08-29 (ClinicalTrials.gov API v2; PubMed E-utilities). Registration or publication volume measures research activity, not effectiveness or approval. Educational information — not medical advice; verify product, indication, legal pathway and evidence with an independent qualified physician. Page generated 2026-08-29. See our editorial standards.
More on this condition
- Premature Ovarian Insufficiency: cell-therapy evidence and registered trials
- How much does stem cell therapy for Premature Ovarian Insufficiency cost? (2026)
- Premature Ovarian Insufficiency stem cell therapy — your questions answered (2026)
- Premature Ovarian Insufficiency: cell-therapy evidence by therapy class
- MSC vs PRP for Premature Ovarian Insufficiency: what the registries show