Open dataset · retrieved 2026-08-05

Where stem-cell research is growing — and where it stalled

2,579 registered studies across 42 conditions, counted by the year each was first posted to ClinicalTrials.gov. Registry counts are usually published as a single current number; this tracks the direction of travel, which is what tells you whether a field is still moving.

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What the registry shows

Comparing the last five complete years with the five before them, 10 of 42 conditions registered materially more new studies and 17 registered materially fewer.

Accelerating: Parkinson's Disease (14→40), Muscular Dystrophy (2→10), Multiple Sclerosis (19→26), Crohn's & IBD (25→31).

Slowing: Knee Osteoarthritis (72→50), Cerebral Palsy (20→2), Primary Immunodeficiency (24→10), Spinal Cord Injury (22→11).

Newly registered stem-cell studies per year (all tracked conditions)
2016141
2017159
2018131
2019136
2020130
2021127
2022105
202391
2024134
2025151
2026119

Neither direction is a verdict on whether a therapy works. A rise can reflect funding cycles or registration practice as much as scientific promise; a fall can follow a field consolidating around fewer, larger trials. Registration is an activity signal, not an efficacy signal.

Method

  • Source: ClinicalTrials.gov API v2, one query per condition with intervention "stem cells", retrieved 2026-08-05.
  • Counting: each study falls in the year of its first-posted date. Studies are not deduplicated across conditions, so a trial listed under two conditions appears in both rows.
  • Not measured: enrolment, completion, results, publication or outcome. A registration is a filing, not a finding.
  • Query fidelity: the registry's condition matching is fuzzy; each condition page links the exact stored query so any count here can be reproduced.

By condition

ConditionRegistered totalRecruitingLast 5yPrior 5yChangeFirst study
Anemia53886107112-4%1999
Diabetes (Type 1 & 2)240285668-18%2001
Knee Osteoarthritis166155072-31%2007
Heart Failure & Cardiac Repair125101923-17%2005
Stroke Recovery110132532-22%2005
Multiple Sclerosis92142619+37%2001
Primary Immunodeficiency92131024-58%1999
Liver Cirrhosis8972123-9%2005
Crohn's & IBD89143125+24%2005
Chronic Kidney Disease8891514+7%2003
Parkinson's Disease70154014+186%2009
Spinal Cord Injury7071122-50%2007
ALS (Motor Neurone Disease)65101914+36%2008
Chronic Wounds & Ulcers6081019-47%2004
Peripheral Neuropathy5091315-13%2006
Lupus (SLE)4761414+0%2000
Rheumatoid Arthritis4481113-15%2000
Macular Degeneration & Vision448515-67%2009
Scleroderma (Systemic Sclerosis)4471011-9%2001
Alzheimer's Disease41101017-41%2009
Cerebral Palsy412220-90%2009
Arterial Hypertension35559-44%2001
Erectile Dysfunction356912-25%2010
Back Pain & Disc Degeneration35277+0%2007
Premature Ovarian Insufficiency3521012-17%2007
COPD & Lung Disease3411613-54%2008
Autism Spectrum Disorder26685+60%2011
Muscular Dystrophy264102+400%2009
Tendon & Sports Injuries231510-50%2013
Hair Loss & Restoration17585+60%2015
Male Infertility15443+33%2010
Ulcerative Colitis15145-20%2010
Osteoporosis & Bone Health14255+0%2006
Hip Osteoarthritis12328-75%2011
Long COVID112100no prior period2021
Psoriasis11027-71%2014
Aesthetic & Anti-Ageing10032+50%2013
Menopause & Hormonal Health10032+50%2003
Spinal Muscular Atrophy5112-50%2009
Intellectual Disability2110no prior period2013
Complex Regional Pain Syndrome2001-100%2007
Fibromyalgia & Chronic Fatigue1001-100%2016

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