Anemia: cell-therapy evidence by therapy class
Across every stem-cell intervention, ClinicalTrials.gov holds 195 registered records for Anemia — 32 recruiting, 14 at Phase 3 or 4, in 15 countries. Snapshot 2026-08-29.
The condition, and why cells are proposed
Under 'anaemia' the registry mostly holds aplastic anaemia and marrow-failure syndromes, where haematopoietic transplantation is not experimental at all — it is standard care with decades of protocol refinement. Mesenchymal cells appear alongside it as a graft-support and graft-versus-host-disease adjunct, which is a different and much less settled question.
Therapy classes side by side
Counts come from separate registry queries per class; a study testing two interventions can appear in more than one row, so rows do not sum to the all-interventions total.
Geography of the research
United States accounts for about 75% of country mentions among sampled studies; 15 countries host at least one site.
| Country | Studies with a site there |
|---|---|
| United States | 132 |
| China | 18 |
| France | 6 |
| South Korea | 5 |
| Brazil | 4 |
| United Kingdom | 4 |
| Russia | 2 |
| Canada | 2 |
The largest registered studies
Sorted by planned enrolment — size is not quality, but a 300-participant trial can answer questions a 12-participant series cannot.
| Study | Phase | Status | Planned n | Lead sponsor | Start |
|---|---|---|---|---|---|
| NCT06065852 — National Registry of Rare Kidney Diseases | n/a | Recruiting | 35,000 | UK Kidney Association | 2009-11-06 |
| NCT00212407 — New York Blood Center National Cord Blood Program | Early Phase 1 | Terminated | 4,476 | New York Blood Center | 1993-02 |
| NCT07205523 — High-Altitude Hematology Observation-Stem Cell Transplantation (HALO-SCT) | n/a | Recruiting | 1,000 | Yigeng Cao,MD,PhD | 2023-09-01 |
| NCT00964821 — Flu Vaccine in Preventing Influenza Infection in Healthy Volunteers and in Patients Who Have Undergone Stem Cell Transplant | n/a | Completed | 459 | City of Hope Medical Center | 2007-01 |
| NCT00003816 — Combination Chemotherapy and Donor Stem Cell Transplant in Treating Patients With Aplastic Anemia or Hematologic Cancer | Phase 2, Phase 3 | Completed | 361 | Roswell Park Cancer Institute | 1998-10-19 |
| NCT00701844 — Sharing Our Strength: A Research Study for Bone Marrow/Stem Cell Transplant Survivors | n/a | Completed | 315 | University of North Carolina, Chapel Hill | 2007-07 |
Most recently registered
| Study | Phase | Status | Planned n | Lead sponsor | Start |
|---|---|---|---|---|---|
| NCT06940570 — Methadone as an Alternative Treatment for Children Underdoing HSCT | n/a | Suspended | n/a | University of Texas Southwestern Medical Center | 2028-01-01 |
| NCT07408583 — Prenatal Transplantation for Fetuses With Fanconi Anemia | n/a | Not Yet Recruiting | n/a | Agnieszka Czechowicz | 2028-01 |
| NCT07737262 — Prophylactic NAC to Improve Platelet Engraftment After Haploidentical Transplantation in Severe Aplastic Anemia Patients | n/a | Not Yet Recruiting | n/a | Peking University People's Hospital | 2026-08-01 |
| NCT07712562 — A Phase 1/2 Study to Evaluate the Safety and Efficacy of Dibotatug (DR-01) in Adults With Bone Marrow Failure Syndromes | n/a | Not Yet Recruiting | n/a | Dren Bio | 2026-08 |
| NCT07698080 — Dexamethasone, Intravenous Injection of Human Immunoglobulin, and Increased Infusion of Mononuclear Cells to Reduce Donor Specific Antibodies in Haplo | n/a | Not Yet Recruiting | n/a | Hematology department of the 920th hospital | 2026-07-03 |
Reading this honestly
Registration counts measure activity, not effect. A study appears here the moment it is registered — before any participant is enrolled, and regardless of whether results are ever posted. For Anemia specifically, the practical question is which registered study — if any — matches the product a provider is offering, and what its outcome measures actually are.
Frequently asked
How many stem-cell trials exist for Anemia?
195 registered records mention a stem-cell intervention for this condition (2026-08-29 snapshot), of which 32 were recruiting.
Which therapy class is furthest along for Anemia?
Ranked by Phase 3/4 records: HSCT (12), MSC (1), exosomes (0), PRP (0).
Does a recruiting trial mean I can be treated?
No. Trials have eligibility criteria, and joining one is not the same as buying a treatment. Paying a clinic for an unproven intervention outside a registered study gives you neither the protections nor the data collection of a trial.
Registry and literature counts retrieved 2026-08-29 (ClinicalTrials.gov API v2; PubMed E-utilities). Registration or publication volume measures research activity, not effectiveness or approval. Educational information — not medical advice; verify product, indication, legal pathway and evidence with an independent qualified physician. Page generated 2026-08-29. See our editorial standards.
Download the query data
Query totals are full API matches; status, phase and country counts describe the first up to 400 returned records per query. Query classes overlap and must not be summed as unique trials. Counts are not treatment outcomes. Snapshot: 2026-08-29. Methods and field definitions.