Arterial Hypertension: cell-therapy evidence by therapy class
Across every stem-cell intervention, ClinicalTrials.gov holds 35 registered records for Arterial Hypertension — 5 recruiting, 5 at Phase 3 or 4, in 13 countries. Snapshot 2026-08-29.
The condition, and why cells are proposed
Resistant hypertension is a plumbing-and-signalling problem: vascular stiffness, renal sodium handling and sympathetic tone. Cell approaches are studied mostly for endothelial repair and inflammation, usually as an add-on to drugs rather than a replacement. Blood pressure is also the most placebo-responsive vital sign in medicine, which shapes how these trials must be designed.
Therapy classes side by side
Counts come from separate registry queries per class; a study testing two interventions can appear in more than one row, so rows do not sum to the all-interventions total.
Geography of the research
United States accounts for about 43% of country mentions among sampled studies; 13 countries host at least one site.
| Country | Studies with a site there |
|---|---|
| United States | 13 |
| China | 6 |
| Brazil | 2 |
| Canada | 2 |
| Colombia | 2 |
| Taiwan | 1 |
| Mexico | 1 |
| Russia | 1 |
The largest registered studies
Sorted by planned enrolment — size is not quality, but a 300-participant trial can answer questions a 12-participant series cannot.
| Study | Phase | Status | Planned n | Lead sponsor | Start |
|---|---|---|---|---|---|
| NCT03011541 — Stem Cell Ophthalmology Treatment Study II | n/a | Recruiting | 500 | MD Stem Cells | 2016-01 |
| NCT07157670 — Cardiovascular Complications in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation. | n/a | Not Yet Recruiting | 400 | Assistance Publique - Hôpitaux de Paris | 2025-09-15 |
| NCT01920867 — Stem Cell Ophthalmology Treatment Study | n/a | Unknown | 300 | MD Stem Cells | 2012-08 |
| NCT07613099 — Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT Imaging | Phase 3 | Recruiting | 210 | National Heart, Lung, and Blood Institute (NHLBI) | 2026-09-02 |
| NCT01155128 — Effects of an Exercise Program in Patients With Hypertensive Chronic Kidney Disease | Phase 4 | Unknown | 200 | Federal University of Pelotas | 2011-09 |
| NCT03562715 — microRNAs Role in Pre-eclampsia Diagnosis | n/a | Completed | 200 | Cairo University | 2016-11-28 |
Most recently registered
| Study | Phase | Status | Planned n | Lead sponsor | Start |
|---|---|---|---|---|---|
| NCT07613099 — Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT Imaging | n/a | Recruiting | n/a | National Heart, Lung, and Blood Institute (NHLBI) | 2026-09-02 |
| NCT07157670 — Cardiovascular Complications in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation. | n/a | Not Yet Recruiting | n/a | Assistance Publique - Hôpitaux de Paris | 2025-09-15 |
| NCT07119580 — Association Between Limbal Function and Tear Proteomics in Chronic Ocular Diseases: Focusing on Glaucoma | n/a | Recruiting | n/a | National Taiwan University Hospital | 2025-07-08 |
| NCT06498440 — Efficacy of NSAID vs. Steroid-NSAID Combo Post-Selective Laser Trabeculoplasty: Phase 4, Single-Center RCT | n/a | Unknown | n/a | St. Joseph's Healthcare Hamilton | 2024-09-01 |
| NCT07183384 — MSC Exosome Therapy for Post-Preeclampsia Endothelial Dysfunction | n/a | Recruiting | n/a | Universitas Padjadjaran | 2024-07-01 |
Reading this honestly
These figures describe effort, not outcome. Published results, with their control arms and endpoints, are where benefit is decided. For Arterial Hypertension specifically, the practical question is which registered study — if any — matches the product a provider is offering, and what its outcome measures actually are.
Frequently asked
How many stem-cell trials exist for Arterial Hypertension?
35 registered records mention a stem-cell intervention for this condition (2026-08-29 snapshot), of which 5 were recruiting.
Which therapy class is furthest along for Arterial Hypertension?
Ranked by Phase 3/4 records: HSCT (1), MSC (0), exosomes (0), PRP (0).
Does a recruiting trial mean I can be treated?
No. Trials have eligibility criteria, and joining one is not the same as buying a treatment. Paying a clinic for an unproven intervention outside a registered study gives you neither the protections nor the data collection of a trial.
Registry and literature counts retrieved 2026-08-29 (ClinicalTrials.gov API v2; PubMed E-utilities). Registration or publication volume measures research activity, not effectiveness or approval. Educational information — not medical advice; verify product, indication, legal pathway and evidence with an independent qualified physician. Page generated 2026-08-29. See our editorial standards.
Download the query data
Query totals are full API matches; status, phase and country counts describe the first up to 400 returned records per query. Query classes overlap and must not be summed as unique trials. Counts are not treatment outcomes. Snapshot: 2026-08-29. Methods and field definitions.