Menopause & Hormonal Health: cell-therapy evidence by therapy class
Across every stem-cell intervention, ClinicalTrials.gov holds 10 registered records for Menopause & Hormonal Health — 0 recruiting, 1 at Phase 3 or 4, in 10 countries. Snapshot 2026-08-29.
The condition, and why cells are proposed
Menopause is a physiological transition, not a disease, and registry entries here mostly concern ovarian function and menopausal symptoms rather than reversal of the transition. The commercial framing of 'ovarian rejuvenation' runs far ahead of what registered studies attempt.
Therapy classes side by side
| Therapy class | Registered | Recruiting | Phase 3/4 | Countries |
|---|---|---|---|---|
| MSC | 1 | 0 | 0 | 1 |
| HSCT | 2 | 0 | 0 | 1 |
| exosomes | 0 | 0 | 0 | 0 |
| PRP | 13 | 2 | 2 | 10 |
Counts come from separate registry queries per class; a study testing two interventions can appear in more than one row, so rows do not sum to the all-interventions total.
Geography of the research
United States accounts for about 25% of country mentions among sampled studies; 10 countries host at least one site.
| Country | Studies with a site there |
|---|---|
| United States | 3 |
| Malta | 1 |
| North Macedonia | 1 |
| Serbia | 1 |
| Brazil | 1 |
| China | 1 |
| Poland | 1 |
| France | 1 |
The largest registered studies
Sorted by planned enrolment — size is not quality, but a 300-participant trial can answer questions a 12-participant series cannot.
| Study | Phase | Status | Planned n | Lead sponsor | Start |
|---|---|---|---|---|---|
| NCT01155128 — Effects of an Exercise Program in Patients With Hypertensive Chronic Kidney Disease | Phase 4 | Unknown | 200 | Federal University of Pelotas | 2011-09 |
| NCT00429455 — Survey of the Need for Information on Fertility and Menopause-Related Treatment Effects Among HSCT Patients | n/a | Completed | 196 | M.D. Anderson Cancer Center | 2007-03 |
| NCT05318989 — Genetic Aspects of Vaginal Aging | n/a | Completed | 120 | Żelazna Medical Centre, LLC | 2021-02-08 |
| NCT04009473 — Stem Cell Therapy and Growth Factor Ovarian in Vitro Activation | Phase 1, Phase 2 | Unknown | 100 | Forever Young d.o.o. | 2019-06-01 |
| NCT00668252 — Circulating Endothelium Progenitor Cells and Endogenous Oestrogen in Healthy Subjects | n/a | Completed | 48 | Assistance Publique - Hôpitaux de Paris | 2006-04 |
| NCT07511660 — Intra Ovarian Muse Cell Injection for Perimenopause Symptom Relief and Ovarian Function Restoration (MUSE-OVARY) | n/a | Enrolling By Invitation | 12 | Healing Hope International | 2026-06-01 |
Most recently registered
| Study | Phase | Status | Planned n | Lead sponsor | Start |
|---|---|---|---|---|---|
| NCT07511660 — Intra Ovarian Muse Cell Injection for Perimenopause Symptom Relief and Ovarian Function Restoration (MUSE-OVARY) | n/a | Enrolling By Invitation | n/a | Healing Hope International | 2026-06-01 |
| NCT06949137 — Intravenous Infusion of Human Mesenchymal Stem Cells (HMM910 ) in Postmenopausal Women With Osteoporosis at High Risk of Fracture | n/a | Active Not Recruiting | n/a | HELP Therapeutics Co., Ltd. | 2025-06-20 |
| NCT07093190 — Stem Cell Recruitment in Exercised Skeletal Muscles of Older Women by Phytosteroid Rg1 | n/a | Completed | n/a | University of Taipei | 2022-03-18 |
| NCT05318989 — Genetic Aspects of Vaginal Aging | n/a | Completed | n/a | Żelazna Medical Centre, LLC | 2021-02-08 |
| NCT04009473 — Stem Cell Therapy and Growth Factor Ovarian in Vitro Activation | n/a | Unknown | n/a | Forever Young d.o.o. | 2019-06-01 |
Reading this honestly
Treat this as a map of research activity. It tells you whether a claim has an evidence programme behind it — not whether the treatment helped anyone. For Menopause & Hormonal Health specifically, the practical question is which registered study — if any — matches the product a provider is offering, and what its outcome measures actually are.
Frequently asked
How many stem-cell trials exist for Menopause & Hormonal Health?
10 registered records mention a stem-cell intervention for this condition (2026-08-29 snapshot), of which 0 were recruiting.
Which therapy class is furthest along for Menopause & Hormonal Health?
Ranked by Phase 3/4 records: PRP (2), MSC (0), HSCT (0), exosomes (0).
Does a recruiting trial mean I can be treated?
No. Trials have eligibility criteria, and joining one is not the same as buying a treatment. Paying a clinic for an unproven intervention outside a registered study gives you neither the protections nor the data collection of a trial.
Registry and literature counts retrieved 2026-08-29 (ClinicalTrials.gov API v2; PubMed E-utilities). Registration or publication volume measures research activity, not effectiveness or approval. Educational information — not medical advice; verify product, indication, legal pathway and evidence with an independent qualified physician. Page generated 2026-08-29. See our editorial standards.
Download the query data
Query totals are full API matches; status, phase and country counts describe the first up to 400 returned records per query. Query classes overlap and must not be summed as unique trials. Counts are not treatment outcomes. Snapshot: 2026-08-29. Methods and field definitions.