Stroke Recovery: cell-therapy evidence by therapy class
Across every stem-cell intervention, ClinicalTrials.gov holds 110 registered records for Stroke Recovery — 12 recruiting, 6 at Phase 3 or 4, in 22 countries. Snapshot 2026-08-29.
The condition, and why cells are proposed
After ischaemic stroke, some recovery happens spontaneously through oedema resolution and cortical reorganisation, mostly in the first three to six months. Cell therapy is studied both acutely for neuroprotection and chronically for plasticity support — and that spontaneous recovery window is the reason early uncontrolled results in this indication are so often misleading.
Therapy classes side by side
Counts come from separate registry queries per class; a study testing two interventions can appear in more than one row, so rows do not sum to the all-interventions total.
Geography of the research
China accounts for about 31% of country mentions among sampled studies; 22 countries host at least one site.
| Country | Studies with a site there |
|---|---|
| China | 28 |
| United States | 24 |
| Taiwan | 8 |
| India | 8 |
| United Kingdom | 5 |
| France | 5 |
| Spain | 4 |
| South Korea | 4 |
The largest registered studies
Sorted by planned enrolment — size is not quality, but a 300-participant trial can answer questions a 12-participant series cannot.
| Study | Phase | Status | Planned n | Lead sponsor | Start |
|---|---|---|---|---|---|
| NCT03899298 — Safety and Clinical Outcomes With Amniotic and Umbilical Cord Tissue Therapy for Numerous Medical Conditions | Phase 1 | Not Yet Recruiting | 5,000 | R3 Stem Cell | 2019-09-01 |
| NCT02795052 — Neurologic Stem Cell Treatment Study | n/a | Recruiting | 500 | MD Stem Cells | 2016-06 |
| NCT03545607 — MultiStem® Administration for Stroke Treatment and Enhanced Recovery Study | Phase 3 | Terminated | 206 | Healios K.K. | 2018-07-28 |
| NCT02980354 — Bayraktutan Dunhill Medical Trust EPC Study | n/a | Unknown | 200 | University of Nottingham | 2017-02-01 |
| NCT02448641 — Study of Modified Stem Cells (SB623) in Patients With Chronic Motor Deficit From Ischemic Stroke | Phase 2 | Completed | 163 | SanBio, Inc. | 2016-03-08 |
| NCT05955326 — Study to Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke | Phase 4 | Recruiting | 160 | Pharmazz, Inc. | 2024-01-08 |
Most recently registered
| Study | Phase | Status | Planned n | Lead sponsor | Start |
|---|---|---|---|---|---|
| NCT07709845 — CC-101 (f/k/a NR1) Neural Stem Cell Transplantation for Adults With Chronic Ischemic Stroke | n/a | Not Yet Recruiting | n/a | Clarion Cells, Inc. | 2027-01 |
| NCT03176498 — Human Umbilical Cord Mesenchymal Stem Cell Therapy (19#iSCLife®-CI) for Cerebral Infarction Patients in Convalescent Period. | n/a | Suspended | n/a | Sclnow Biotechnology Co., Ltd. | 2026-12-31 |
| NCT03186456 — The Safety and Efficacy of Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-ACI) in the Treatment of Acute Cerebral Infarction | n/a | Suspended | n/a | Sclnow Biotechnology Co., Ltd. | 2026-12-31 |
| NCT07731087 — MSC Secretome Therapy for Cognitive Recovery After Subacute Ischemic Stroke | n/a | Recruiting | n/a | Jumraini Tammasse | 2026-07-09 |
| NCT07628933 — A Phase I Trial of Umbilical Cord Mesenchymal Stromal Cells for Acute Ischemic Stroke | n/a | Not Yet Recruiting | n/a | BOE Technology Group Co., Ltd. | 2026-06-30 |
Reading this honestly
Treat this as a map of research activity. It tells you whether a claim has an evidence programme behind it — not whether the treatment helped anyone. For Stroke Recovery specifically, the practical question is which registered study — if any — matches the product a provider is offering, and what its outcome measures actually are.
Frequently asked
How many stem-cell trials exist for Stroke Recovery?
110 registered records mention a stem-cell intervention for this condition (2026-08-29 snapshot), of which 12 were recruiting.
Which therapy class is furthest along for Stroke Recovery?
Ranked by Phase 3/4 records: MSC (3), HSCT (0), exosomes (0), PRP (0).
Does a recruiting trial mean I can be treated?
No. Trials have eligibility criteria, and joining one is not the same as buying a treatment. Paying a clinic for an unproven intervention outside a registered study gives you neither the protections nor the data collection of a trial.
Registry and literature counts retrieved 2026-08-29 (ClinicalTrials.gov API v2; PubMed E-utilities). Registration or publication volume measures research activity, not effectiveness or approval. Educational information — not medical advice; verify product, indication, legal pathway and evidence with an independent qualified physician. Page generated 2026-08-29. See our editorial standards.
Download the query data
Query totals are full API matches; status, phase and country counts describe the first up to 400 returned records per query. Query classes overlap and must not be summed as unique trials. Counts are not treatment outcomes. Snapshot: 2026-08-29. Methods and field definitions.