How many stem-cell trials for Crohn's & IBD are recruiting right now?
The registry lists 14 studies actively recruiting out of 89 records in total (16%), as of 2026-08-29.
Who these studies will actually take
Fistula studies require imaging-confirmed anatomy and controlled luminal disease; luminal trials require endoscopic activity scores and often failure of biologics. Both exclude active infection or abscess, which is common at the point people start searching.
The studies currently enrolling
| Study | Phase | Status | Planned n | Lead sponsor | Start |
|---|---|---|---|---|---|
| NCT05039411 — Safety of Allogeneic Human Umbilical Cord Mesenchymal Stem Cells (UC-MSCs) to Treat Perianal Fistulas w/ Crohn's Disease | Phase 1 | Recruiting | 5 | CryoCord Sdn Bhd | 2022-03-01 |
| NCT03219359 — Autologous Stem Cell Transplant for Crohn's Disease | Phase 2 | Recruiting | 50 | Aaron Etra | 2018-02-22 |
| NCT04528355 — Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC | n/a | Recruiting | 50 | Paul Szabolcs | 2020-08-20 |
| NCT05294107 — Intestinal Organoids | n/a | Recruiting | 90 | Rennes University Hospital | 2022-09-06 |
| NCT04224558 — Stem Cell Transplantation in Crohn's Disease | Phase 1, Phase 2 | Recruiting | 15 | Cedars-Sinai Medical Center | 2019-11-15 |
| NCT06636032 — Dose Escalation of Allogeneic Adipose Derived Stroma/Stem Cells for the Treatment of Crohn's Fistula | Phase 1, Phase 2 | Recruiting | 9 | University Hospital, Toulouse | 2025-03-12 |
| NCT03901235 — MSC Intratissular Injection in Crohn Disease Patients | Phase 1, Phase 2 | Recruiting | 60 | University of Liege | 2018-01-15 |
| NCT06925594 — Phase 3 Study of Human TH-SC01 Cell Injection for Treating Perianal Fistulas in Patients With Crohn's Disease | Phase 3 | Recruiting | 228 | Jiangsu Topcel-KH Pharmaceutical Co., Ltd. | 2025-03-20 |
What recruiting does and does not mean
Recruiting means a sponsor has an approved protocol and is looking for participants who meet specific criteria. It does not mean the therapy is on sale, that you qualify, or that earlier studies were positive. Records are also left as recruiting after enrolment stalls, so the contact block on the registry page matters more than the label.
Sites sit in 26 countries, led by United States. Travelling for a trial rarely works unless the site has confirmed in writing that it can enrol non-residents and fund the follow-up schedule.
Who is running the studies here
Lead sponsors appearing most often for this condition. Useful for one specific check: whether the entity quoting research at you appears anywhere in it.
- Anterogen Co., Ltd. — 5 registered records
- Tigenix S.A.U. — 5 registered records
- Anthony Lembo — 5 registered records
- Mesoblast, Inc. — 4 registered records
- Direct Biologics, LLC — 3 registered records
- Takeda — 3 registered records
Frequently asked
How many stem-cell trials for Crohn's & IBD are recruiting right now?
14 of 89 registered records (2026-08-29).
Can I join one of these trials?
Only if you meet the published eligibility criteria and the site confirms capacity. Start from the registry record's contact block, not from a clinic advertisement.
Do trials charge participants?
Trial participation is normally free of charge for the intervention under study; some studies even reimburse travel. Payment demands invert that relationship and should stop the conversation.
Registry and literature counts retrieved 2026-08-29 (ClinicalTrials.gov API v2; PubMed E-utilities). Registration or publication volume measures research activity, not effectiveness or approval. Educational information — not medical advice; verify product, indication, legal pathway and evidence with an independent qualified physician. Page generated 2026-08-29. See our editorial standards.