Question

Which countries run stem-cell trials for Multiple Sclerosis?

Sampled registrations place sites in 31 countries. United States is the largest single contributor at roughly 46% of country mentions. Snapshot 2026-08-29.

Medical review statusMedically reviewedReviewed by: Stem Plus medical teamReviewed on: 2026-08-29Last evidence update: 2026-08-29Methodology and editorial standards
Clinical review team: Dr Kamelia Milcheva, Hematologist · Dr Vadym Uvarov, Board-Certified Physician · Hepatobiliary Surgeon · Candidate of Medical SciencesEditorial responsibility: StemCellAtlas research teamEducational information only. This page does not provide medical advice, diagnosis or a treatment recommendation.

Country distribution

CountryStudies with a site there
United States31
Italy6
United Kingdom6
Spain5
Sweden5
Canada4
Jordan3
Trinidad and Tobago3
Russia2
Iran2

A study with sites in several countries is counted once per country, taken from the location block of each registry record.

What the map means for Multiple Sclerosis

Transplant work concentrates in accredited haematology units in Europe, North America and a few other centres, with published registry outcomes. Commercial mesenchymal offers cluster in tourism markets and do not carry that accreditation or reporting.

Where recruitment is actually open

CountryOpen studies with a site there
Italy3
United Arab Emirates1
United States1
Russia1
Canada1
United Kingdom1
Taiwan1
Netherlands1

What travelling for a trial actually involves

Distance changes the risk calculus. Registered studies are designed around continuity of care, so a site will normally decline participants it cannot monitor — which is exactly the safeguard a commercial clinic does not apply.

Multi-country studies, named

Registered studies with sites in more than one country — the clearest evidence of collaboration rather than a single-centre series.

  • NCT06665165 — AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis (Canada, United States)
  • NCT05003388 — Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for MS (Antigua and Barbuda, Greece)

Why trial geography is not a shortlist

Trial locations follow regulation, funding and sponsor headquarters, not clinical quality. Countries with clear conditional pathways for advanced therapies and large public research budgets register more studies. A country appearing here also says nothing about whether commercial clinics there operate under the same oversight as the registered trials.

Before treating geography as a shortlist, read the legality overview by country and what "best country" actually means here.

When these studies started

Registrations by start year since 2020: 2020 (4), 2021 (8), 2022 (1), 2023 (5), 2025 (5), 2026 (4). Activity for this condition spans 1997 to 2026, which shows whether interest is growing, flat or past its peak.

Frequently asked

Which countries run stem-cell trials for Multiple Sclerosis?

Sites are registered in 31 countries; the largest is United States (~46% of country mentions, 2026-08-29).

Does a country with many trials mean better treatment there?

It does not follow. A country can host many trials and still have an unregulated commercial sector selling something quite different to visitors.

Are trial sites and commercial clinics the same thing?

Usually not. The hospital running a registered study is often unrelated to clinics marketing treatments to international patients in the same city.

Registry and literature counts retrieved 2026-08-29 (ClinicalTrials.gov API v2; PubMed E-utilities). Registration or publication volume measures research activity, not effectiveness or approval. Educational information — not medical advice; verify product, indication, legal pathway and evidence with an independent qualified physician. Page generated 2026-08-29. See our editorial standards.

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