Which countries run stem-cell trials for Multiple Sclerosis?
Sampled registrations place sites in 31 countries. United States is the largest single contributor at roughly 46% of country mentions. Snapshot 2026-08-29.
Country distribution
| Country | Studies with a site there |
|---|---|
| United States | 31 |
| Italy | 6 |
| United Kingdom | 6 |
| Spain | 5 |
| Sweden | 5 |
| Canada | 4 |
| Jordan | 3 |
| Trinidad and Tobago | 3 |
| Russia | 2 |
| Iran | 2 |
A study with sites in several countries is counted once per country, taken from the location block of each registry record.
What the map means for Multiple Sclerosis
Transplant work concentrates in accredited haematology units in Europe, North America and a few other centres, with published registry outcomes. Commercial mesenchymal offers cluster in tourism markets and do not carry that accreditation or reporting.
Where recruitment is actually open
| Country | Open studies with a site there |
|---|---|
| Italy | 3 |
| United Arab Emirates | 1 |
| United States | 1 |
| Russia | 1 |
| Canada | 1 |
| United Kingdom | 1 |
| Taiwan | 1 |
| Netherlands | 1 |
What travelling for a trial actually involves
Distance changes the risk calculus. Registered studies are designed around continuity of care, so a site will normally decline participants it cannot monitor — which is exactly the safeguard a commercial clinic does not apply.
Multi-country studies, named
Registered studies with sites in more than one country — the clearest evidence of collaboration rather than a single-centre series.
- NCT06665165 — AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis (Canada, United States)
- NCT05003388 — Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for MS (Antigua and Barbuda, Greece)
Why trial geography is not a shortlist
Trial locations follow regulation, funding and sponsor headquarters, not clinical quality. Countries with clear conditional pathways for advanced therapies and large public research budgets register more studies. A country appearing here also says nothing about whether commercial clinics there operate under the same oversight as the registered trials.
Before treating geography as a shortlist, read the legality overview by country and what "best country" actually means here.
When these studies started
Registrations by start year since 2020: 2020 (4), 2021 (8), 2022 (1), 2023 (5), 2025 (5), 2026 (4). Activity for this condition spans 1997 to 2026, which shows whether interest is growing, flat or past its peak.
Frequently asked
Which countries run stem-cell trials for Multiple Sclerosis?
Sites are registered in 31 countries; the largest is United States (~46% of country mentions, 2026-08-29).
Does a country with many trials mean better treatment there?
It does not follow. A country can host many trials and still have an unregulated commercial sector selling something quite different to visitors.
Are trial sites and commercial clinics the same thing?
Usually not. The hospital running a registered study is often unrelated to clinics marketing treatments to international patients in the same city.
Registry and literature counts retrieved 2026-08-29 (ClinicalTrials.gov API v2; PubMed E-utilities). Registration or publication volume measures research activity, not effectiveness or approval. Educational information — not medical advice; verify product, indication, legal pathway and evidence with an independent qualified physician. Page generated 2026-08-29. See our editorial standards.
More on this condition
- Multiple Sclerosis: cell-therapy evidence and registered trials
- How much does stem cell therapy for Multiple Sclerosis cost? (2026)
- Multiple Sclerosis stem cell therapy — your questions answered (2026)
- Multiple Sclerosis: cell-therapy evidence by therapy class
- MSC vs HSCT for Multiple Sclerosis: what the registries show