Autoimmune and inflammatory
Immune modulation is biologically plausible, but the word covers everything from intensive immune ablation and transplant to short-lived paracrine signalling from an MSC product.
What the registry pattern says
Crohn's disease has the largest MSC registry footprint in this group (52 query results; 6 recruiting in the stored snapshot). Rheumatoid Arthritis has the largest exosome footprint (4). These are query-result counts, not deduplicated patients or proof of benefit.
Ask whether the intervention aims to reset, suppress or temporarily modulate immunity, and compare that goal with established disease-modifying care.
Condition × therapy-class snapshot
| Condition | MSC | MSC recruiting | HSCT-family | Exosomes |
|---|---|---|---|---|
| Crohn's disease | 52 | 6 | 18 | 2 |
| Lupus | 23 | 4 | 17 | 2 |
| Psoriasis | 10 | 0 | 0 | 1 |
| Rheumatoid Arthritis | 22 | 2 | 11 | 4 |
| Scleroderma | 0 | 0 | 0 | 0 |
| Ulcerative Colitis | 0 | 0 | 0 | 0 |
Source: ClinicalTrials.gov API v2 stored snapshot. Category totals add query results and may contain overlapping studies; use condition pages for interpretation.
Interactive/editorial page by the StemCellAtlas research team. Where registry or literature counts appear, they use the dated 2026-08-29 snapshot. Browser-only tools do not send or store answers. Page generated 2026-08-29. See our editorial standards.