Erectile Dysfunction: cell-therapy evidence by therapy class
Across every stem-cell intervention, ClinicalTrials.gov holds 35 registered records for Erectile Dysfunction — 6 recruiting, 2 at Phase 3 or 4, in 16 countries. Snapshot 2026-08-29.
The condition, and why cells are proposed
Erectile dysfunction is usually vascular and endothelial rather than structural, which is why regenerative approaches — cells, exosomes and shockwave adjuncts — target penile blood flow and nerve recovery. Post-prostatectomy nerve injury is a separate problem with a different time course, and the two are frequently blurred together in marketing.
Therapy classes side by side
Counts come from separate registry queries per class; a study testing two interventions can appear in more than one row, so rows do not sum to the all-interventions total.
Geography of the research
United States accounts for about 28% of country mentions among sampled studies; 16 countries host at least one site.
| Country | Studies with a site there |
|---|---|
| United States | 7 |
| South Korea | 4 |
| China | 4 |
| Denmark | 2 |
| Jordan | 2 |
| Indonesia | 2 |
| Kazakhstan | 1 |
| United Arab Emirates | 1 |
The largest registered studies
Sorted by planned enrolment — size is not quality, but a 300-participant trial can answer questions a 12-participant series cannot.
| Study | Phase | Status | Planned n | Lead sponsor | Start |
|---|---|---|---|---|---|
| NCT04684602 — Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions | Phase 1, Phase 2 | Recruiting | 5,000 | Thomas Advanced Medical LLC | 2020-07-09 |
| NCT03899298 — Safety and Clinical Outcomes With Amniotic and Umbilical Cord Tissue Therapy for Numerous Medical Conditions | Phase 1 | Not Yet Recruiting | 5,000 | R3 Stem Cell | 2019-09-01 |
| NCT01953523 — Safety and Clinical Outcomes Study: SVF Deployment for Orthopedic, Neurologic, Urologic, and Cardio-pulmonary Conditions | n/a | Completed | 3,000 | Elliot Lander | 2013-09-02 |
| NCT07544537 — A Prospective Comparative Study of Autologous Bone Marrow-Derived and Adipose Tissue-Derived Mesenchymal Stem Cells Versus Platelet-Rich Plasma and St | Phase 2 | Active Not Recruiting | 100 | National Scientific Medical Center, Kazakhstan | 2024-09-09 |
| NCT07480161 — Mesenchymal Stem Cell and Exosome Therapy for Diabetic Erectile Dysfunction | Phase 2, Phase 3 | Recruiting | 90 | Ankara City Hospital Bilkent | 2025-12-29 |
| NCT07319533 — Clinical Trial Investigating the Effect of Exosomes as a Complementary Treatment in Severe to Moderate Erectile Dysfunction | Phase 2 | Not Yet Recruiting | 70 | Labbafinejad Medical Center | 2026-01 |
Most recently registered
| Study | Phase | Status | Planned n | Lead sponsor | Start |
|---|---|---|---|---|---|
| NCT07048314 — Stem Cells for Erectile Dysfunction Post RALP | n/a | Recruiting | n/a | The Methodist Hospital Research Institute | 2026-07-07 |
| NCT07319533 — Clinical Trial Investigating the Effect of Exosomes as a Complementary Treatment in Severe to Moderate Erectile Dysfunction | n/a | Not Yet Recruiting | n/a | Labbafinejad Medical Center | 2026-01 |
| NCT07480161 — Mesenchymal Stem Cell and Exosome Therapy for Diabetic Erectile Dysfunction | n/a | Recruiting | n/a | Ankara City Hospital Bilkent | 2025-12-29 |
| NCT06839651 — Umbilical Cord Mesenchymal Stem Cell Secretome in Severe Erectile Dysfunction Non-responsive to Sildenafil | n/a | Not Yet Recruiting | n/a | Indonesia University | 2025-04-21 |
| NCT06605508 — Regenerative Injection of Stem Cells or Stem Cell-derived Exosomes for Erectile Dysfunction (RISE) | n/a | Recruiting | n/a | Jumeirah American Clinic | 2025-01-10 |
Reading this honestly
None of these numbers say the therapy works. They say how much organised research exists and how far along it is; effect sizes live in published results, not registry entries. For Erectile Dysfunction specifically, the practical question is which registered study — if any — matches the product a provider is offering, and what its outcome measures actually are.
Frequently asked
How many stem-cell trials exist for Erectile Dysfunction?
35 registered records mention a stem-cell intervention for this condition (2026-08-29 snapshot), of which 6 were recruiting.
Which therapy class is furthest along for Erectile Dysfunction?
Ranked by Phase 3/4 records: PRP (6), MSC (2), exosomes (1), HSCT (0).
Does a recruiting trial mean I can be treated?
No. Trials have eligibility criteria, and joining one is not the same as buying a treatment. Paying a clinic for an unproven intervention outside a registered study gives you neither the protections nor the data collection of a trial.
Registry and literature counts retrieved 2026-08-29 (ClinicalTrials.gov API v2; PubMed E-utilities). Registration or publication volume measures research activity, not effectiveness or approval. Educational information — not medical advice; verify product, indication, legal pathway and evidence with an independent qualified physician. Page generated 2026-08-29. See our editorial standards.
Download the query data
Query totals are full API matches; status, phase and country counts describe the first up to 400 returned records per query. Query classes overlap and must not be summed as unique trials. Counts are not treatment outcomes. Snapshot: 2026-08-29. Methods and field definitions.