Peripheral Neuropathy: cell-therapy evidence by therapy class
Across every stem-cell intervention, ClinicalTrials.gov holds 50 registered records for Peripheral Neuropathy — 9 recruiting, 2 at Phase 3 or 4, in 16 countries. Snapshot 2026-08-29.
The condition, and why cells are proposed
Peripheral neuropathy covers diabetic, chemotherapy-induced and idiopathic nerve damage with very different prognoses. Cell rationales target microvascular support and nerve regeneration, and unlike the central nervous system, peripheral nerves do regenerate — slowly, and only if the underlying cause is controlled.
Therapy classes side by side
Counts come from separate registry queries per class; a study testing two interventions can appear in more than one row, so rows do not sum to the all-interventions total.
Geography of the research
United States accounts for about 50% of country mentions among sampled studies; 16 countries host at least one site.
| Country | Studies with a site there |
|---|---|
| United States | 21 |
| China | 6 |
| South Korea | 5 |
| Germany | 3 |
| Indonesia | 2 |
| United Arab Emirates | 1 |
| Spain | 1 |
| Antigua and Barbuda | 1 |
The largest registered studies
Sorted by planned enrolment — size is not quality, but a 300-participant trial can answer questions a 12-participant series cannot.
| Study | Phase | Status | Planned n | Lead sponsor | Start |
|---|---|---|---|---|---|
| NCT04684602 — Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions | Phase 1, Phase 2 | Recruiting | 5,000 | Thomas Advanced Medical LLC | 2020-07-09 |
| NCT03899298 — Safety and Clinical Outcomes With Amniotic and Umbilical Cord Tissue Therapy for Numerous Medical Conditions | Phase 1 | Not Yet Recruiting | 5,000 | R3 Stem Cell | 2019-09-01 |
| NCT02795052 — Neurologic Stem Cell Treatment Study | n/a | Recruiting | 500 | MD Stem Cells | 2016-06 |
| NCT02796079 — A Clinical Study Using Autologous Bone Marrow Stem Cell for Diabetes Related Vascular Complications | Phase 1 | Unknown | 240 | Jie Shen | 2015-01 |
| NCT02831075 — A Clinical Study Using Adipose-derived Stem Cells for Diabetic Foot | Phase 1 | Unknown | 240 | Jie Shen | 2015-01 |
| NCT02834858 — Umbilical Cord Mesenchymal Stem Cells Infusion for Diabetes Related Vascular Complications | Phase 1 | Unknown | 240 | Jie Shen | 2016-01 |
Most recently registered
| Study | Phase | Status | Planned n | Lead sponsor | Start |
|---|---|---|---|---|---|
| NCT07686094 — Placental Cells for Diabetic Foot Ulcers | n/a | Not Yet Recruiting | n/a | Wake Forest University Health Sciences | 2026-10 |
| NCT07700316 — Compare the Effect of Radiofrequency (TECAR) and Ultrasound on Sensation, Hand Dexterity, and Quality of Life in Patients With Carpal Tunnel Syndrome. | n/a | Not Yet Recruiting | n/a | Delta University for Science and Technology | 2026-08-01 |
| NCT06625190 — Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors | n/a | Recruiting | n/a | University of Florida | 2026-02-11 |
| NCT07723313 — Effectiveness of Amniotic Membrane Combined With Secretome as an Adjunct to Carpal Tunnel Release Surgery: Evaluation Using the Boston Carpal Tunnel Q | n/a | Recruiting | n/a | PT. Prodia Stem Cell Indonesia | 2025-12-15 |
| NCT07183761 — A Randomized Controlled Trial on the Efficacy and Safety of Umbilical Cord Mesenchymal Stem Cell Therapy in Subjects With Moderate to Severe Diabetic | n/a | Recruiting | n/a | Min Long | 2025-10-01 |
Reading this honestly
These figures describe effort, not outcome. Published results, with their control arms and endpoints, are where benefit is decided. For Peripheral Neuropathy specifically, the practical question is which registered study — if any — matches the product a provider is offering, and what its outcome measures actually are.
Frequently asked
How many stem-cell trials exist for Peripheral Neuropathy?
50 registered records mention a stem-cell intervention for this condition (2026-08-29 snapshot), of which 9 were recruiting.
Which therapy class is furthest along for Peripheral Neuropathy?
Ranked by Phase 3/4 records: PRP (4), HSCT (1), MSC (0), exosomes (0).
Does a recruiting trial mean I can be treated?
No. Trials have eligibility criteria, and joining one is not the same as buying a treatment. Paying a clinic for an unproven intervention outside a registered study gives you neither the protections nor the data collection of a trial.
Registry and literature counts retrieved 2026-08-29 (ClinicalTrials.gov API v2; PubMed E-utilities). Registration or publication volume measures research activity, not effectiveness or approval. Educational information — not medical advice; verify product, indication, legal pathway and evidence with an independent qualified physician. Page generated 2026-08-29. See our editorial standards.
Download the query data
Query totals are full API matches; status, phase and country counts describe the first up to 400 returned records per query. Query classes overlap and must not be summed as unique trials. Counts are not treatment outcomes. Snapshot: 2026-08-29. Methods and field definitions.