Spain, Italy, France, and Germany have active and published MSC therapy programmes for scleroderma. HSCT for scleroderma is performed at major transplant centres worldwide (US, Europe, Asia); the procedure is most established and accessible in France, Germany, and specialised transplant programmes globally.
Placental MSC infusion for scleroderma costs €5,000–8,500 per treatment course, with many protocols involving two to three infusions spaced weeks to months apart. Autologous HSCT is substantially more expensive (€35,000–60,000), reflecting hospitalisation, high-dose chemotherapy conditioning, stem-cell mobilisation and reinfusion, and intensive post-transplant monitoring. Baseline assessments (skin biopsy, pulmonary function, cardiac imaging) add €2,000–3,500. Long-term immunosuppression post-HSCT incurs ongoing medication costs.
Am I a candidate? → · Scleroderma (Systemic Sclerosis): full overview → · Scleroderma (Systemic Sclerosis) cost → · Cost →
Medically reviewed by StemCellAtlas’s editorial team with Dr Polina Krasenova (Haematologist · Clinical Haematology & Integrative Oncology · 15+ yrs cell therapy) of partner clinic Stem Plus (Sofia), against ISSCR, FDA & EMA guidance. Educational information, not medical advice; figures indicative.
StemCellAtlas is your guide to stem-cell therapy: what the evidence shows, which conditions are treated, and the real all-in cost by country — typically €3,000–8,000 with our partner Stem Plus (Sofia), Europe's lowest-cost EU destination, versus $15,000–35,000 in the US.
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